Find Grants for Small Businesses (for-profit)

Find out if you qualify for verified grants for Small Businesses (for-profit). Discover your eligibility and key funding details for Small Businesses (for-profit) from major foundations and government agencies.

$ 100 Trillion
Total Dollars Available

Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

Deadline: January 9, 2029


Opportunity Number: RFA-OD-25-011

Agency: National Institutes of Health

Open Date: December 5, 2025

Close Date: January 9, 2029

Status: Posted

CFDA Numbers: 93.351

Diabetes Research Centers (P30 Clinical Trial Optional)

Deadline: January 27, 2027


Opportunity Number: RFA-DK-26-310

Agency: National Institutes of Health

Open Date: December 5, 2025

Close Date: January 27, 2027

Status: Posted

CFDA Numbers: 93.847

Informatics, Coordination and Service Center for the Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed)

Deadline: May 1, 2026


Opportunity Number: RFA-OD-25-012

Agency: National Institutes of Health

Open Date: December 5, 2025

Close Date: May 1, 2026

Status: Posted

CFDA Numbers: 93.351

Limited Competition Renewal for the Continuation of the Liver Cirrhosis Network: Clinical Research Centers (U01 Clinical Trial Required)

Deadline: March 8, 2027


Opportunity Number: RFA-DK-26-308

Agency: National Institutes of Health

Open Date: December 5, 2025

Close Date: March 8, 2027

Status: Posted

CFDA Numbers: 93.847

Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)

Deadline: September 28, 2028


Opportunity Number: RFA-OD-25-010

Agency: National Institutes of Health

Open Date: December 5, 2025

Close Date: September 28, 2028

Status: Posted

CFDA Numbers: 93.351

Engineering Improved Stem Cell-Derived Islet Cells for Replacement Therapies (R01 - Clinical Trial Not Allowed)

Deadline: March 7, 2026


Opportunity Number: RFA-DK-26-306

Agency: National Institutes of Health

Open Date: December 3, 2025

Close Date: March 7, 2026

Status: Posted

CFDA Numbers: 93.847

Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)

Deadline: February 12, 2026


Opportunity Number: RFA-CA-25-032

Agency: National Institutes of Health

Open Date: December 2, 2025

Close Date: February 12, 2026

Status: Posted

CFDA Numbers: 93.399

Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Deadline: November 30, 2028


Opportunity Number: PA-26-001

Agency: National Institutes of Health

Open Date: November 26, 2025

Close Date: November 30, 2028

Status: Posted

CFDA Numbers: 93.310

Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)

Deadline: September 25, 2028


Opportunity Number: PAR-25-444

Agency: National Institutes of Health

Open Date: November 26, 2025

Close Date: September 25, 2028

Status: Posted

CFDA Numbers: 93.397

F25AS00317 Crane Creek Lacustuary Restoration

Deadline: January 23, 2026


Opportunity Number: F25AS00317

Agency: Fish and Wildlife Service

Open Date: November 19, 2025

Close Date: January 23, 2026

Status: Posted

CFDA Numbers: 15.662

Infrastructure Investment and Jobs Act (IIJA) – Mines & Metals Capacity Expansion – Piloting Byproduct Critical Minerals and Materials Recovery at Domestic Industrial Facilities

Deadline: January 15, 2026


Opportunity Number: DE-FOA-0003583

Agency: National Energy Technology Laboratory

Open Date: November 14, 2025

Close Date: January 15, 2026

Status: Posted

CFDA Numbers: 81.089

Infrastructure Investment and Jobs Act (IIJA): Mine of the Future - Proving Ground Initiative

Deadline: January 30, 2026


Opportunity Number: DE-FOA-0003390

Agency: National Energy Technology Laboratory

Open Date: November 14, 2025

Close Date: January 30, 2026

Status: Posted

CFDA Numbers: 81.089

Improving Efficiency, Reliability, and Flexibility of Coal-Based Power Plants

Deadline: January 7, 2026


Opportunity Number: DE-FOA-0003606

Agency: National Energy Technology Laboratory

Open Date: October 31, 2025

Close Date: January 7, 2026

Status: Posted

CFDA Numbers: 81.089

FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program

Deadline: September 30, 2026


Opportunity Number: DE-FOA-0003600

Agency: Office of Science

Open Date: September 30, 2025

Close Date: September 30, 2026

Status: Posted

CFDA Numbers: 81.049

Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)

Deadline: June 7, 2028


Opportunity Number: PAR-25-449

Agency: National Institutes of Health

Open Date: September 26, 2025

Close Date: June 7, 2028

Status: Posted

CFDA Numbers: 93.213

Dynamic and Adaptable Infrastructure for Drug Development and Outreach to Aid the Research Community in Advancing Medication Repurposing and Repositioning Efforts for Substance Use Disorders (SUDs) (U54 - Clinical Trials Not Allowed)

Deadline: January 28, 2026


Opportunity Number: RFA-DA-26-020

Agency: National Institutes of Health

Open Date: September 24, 2025

Close Date: January 28, 2026

Status: Posted

CFDA Numbers: 93.279

Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)

Deadline: July 20, 2028


Opportunity Number: PAR-25-450

Agency: National Institutes of Health

Open Date: September 22, 2025

Close Date: July 20, 2028

Status: Posted

CFDA Numbers: 93.350, 93.865

NHLBI TOPMed: Omics Phenotypes of Heart, Lung, and Blood Disorders (X01 - Clinical Trial Not Allowed)

Deadline: May 8, 2028


Opportunity Number: PAR-25-447

Agency: National Institutes of Health

Open Date: September 22, 2025

Close Date: May 8, 2028

Status: Posted

CFDA Numbers: 93.837, 93.838, 93.839, 93.840, 93.233

Advancing Research on the Application of Digital Health Technology to the Management of Type 2 Diabetes (R01- Clinical Trail Required)

Deadline: October 6, 2026


Opportunity Number: RFA-DK-26-315

Agency: National Institutes of Health

Open Date: September 17, 2025

Close Date: October 6, 2026

Status: Posted

CFDA Numbers: 93.847

Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional)

Deadline: May 7, 2028


Opportunity Number: PAR-25-439

Agency: National Institutes of Health

Open Date: September 17, 2025

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.361

BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)

Deadline: November 8, 2027


Opportunity Number: RFA-DA-27-004

Agency: National Institutes of Health

Open Date: September 16, 2025

Close Date: November 8, 2027

Status: Posted

CFDA Numbers: 93.213, 93.867, 93.853, 93.866, 93.242, 93.273, 93.279, 93.286, 93.372, 93.173, 93.865

NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)

Deadline: June 2, 2028


Opportunity Number: PAR-25-445

Agency: National Institutes of Health

Open Date: September 15, 2025

Close Date: June 2, 2028

Status: Posted

CFDA Numbers: 93.173

Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

Deadline: August 21, 2028


Opportunity Number: PAR-25-446

Agency: National Institutes of Health

Open Date: September 10, 2025

Close Date: August 21, 2028

Status: Posted

CFDA Numbers: 93.279

F25AS00282 National Fish Passage Program FY25

Deadline: December 31, 2025


Opportunity Number: F25AS00282

Agency: Fish and Wildlife Service

Open Date: September 3, 2025

Close Date: December 31, 2025

Status: Posted

CFDA Numbers: 15.685

NIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program (R25 Independent Clinical Trial Not Allowed)

Deadline: May 26, 2027


Opportunity Number: RFA-AG-26-010

Agency: National Institutes of Health

Open Date: September 2, 2025

Close Date: May 26, 2027

Status: Posted

CFDA Numbers: 93.866

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