Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
Deadline: January 9, 2029
Opportunity Number: RFA-OD-25-011
Agency: National Institutes of Health
Open Date: December 5, 2025
Close Date: January 9, 2029
Status: Posted
CFDA Numbers: 93.351
Diabetes Research Centers (P30 Clinical Trial Optional)
Deadline: January 27, 2027
Opportunity Number: RFA-DK-26-310
Agency: National Institutes of Health
Open Date: December 5, 2025
Close Date: January 27, 2027
Status: Posted
CFDA Numbers: 93.847
Informatics, Coordination and Service Center for the Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed)
Deadline: May 1, 2026
Opportunity Number: RFA-OD-25-012
Agency: National Institutes of Health
Open Date: December 5, 2025
Close Date: May 1, 2026
Status: Posted
CFDA Numbers: 93.351
Limited Competition Renewal for the Continuation of the Liver Cirrhosis Network: Clinical Research Centers (U01 Clinical Trial Required)
Deadline: March 8, 2027
Opportunity Number: RFA-DK-26-308
Agency: National Institutes of Health
Open Date: December 5, 2025
Close Date: March 8, 2027
Status: Posted
CFDA Numbers: 93.847
Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
Deadline: September 28, 2028
Opportunity Number: RFA-OD-25-010
Agency: National Institutes of Health
Open Date: December 5, 2025
Close Date: September 28, 2028
Status: Posted
CFDA Numbers: 93.351
Engineering Improved Stem Cell-Derived Islet Cells for Replacement Therapies (R01 - Clinical Trial Not Allowed)
Deadline: March 7, 2026
Opportunity Number: RFA-DK-26-306
Agency: National Institutes of Health
Open Date: December 3, 2025
Close Date: March 7, 2026
Status: Posted
CFDA Numbers: 93.847
Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)
Deadline: February 12, 2026
Opportunity Number: RFA-CA-25-032
Agency: National Institutes of Health
Open Date: December 2, 2025
Close Date: February 12, 2026
Status: Posted
CFDA Numbers: 93.399
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Deadline: November 30, 2028
Opportunity Number: PA-26-001
Agency: National Institutes of Health
Open Date: November 26, 2025
Close Date: November 30, 2028
Status: Posted
CFDA Numbers: 93.310
Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
Deadline: September 25, 2028
Opportunity Number: PAR-25-444
Agency: National Institutes of Health
Open Date: November 26, 2025
Close Date: September 25, 2028
Status: Posted
CFDA Numbers: 93.397
F25AS00317 Crane Creek Lacustuary Restoration
Deadline: January 23, 2026
Opportunity Number: F25AS00317
Agency: Fish and Wildlife Service
Open Date: November 19, 2025
Close Date: January 23, 2026
Status: Posted
CFDA Numbers: 15.662
Infrastructure Investment and Jobs Act (IIJA) – Mines & Metals Capacity Expansion – Piloting Byproduct Critical Minerals and Materials Recovery at Domestic Industrial Facilities
Deadline: January 15, 2026
Opportunity Number: DE-FOA-0003583
Agency: National Energy Technology Laboratory
Open Date: November 14, 2025
Close Date: January 15, 2026
Status: Posted
CFDA Numbers: 81.089
Infrastructure Investment and Jobs Act (IIJA): Mine of the Future - Proving Ground Initiative
Deadline: January 30, 2026
Opportunity Number: DE-FOA-0003390
Agency: National Energy Technology Laboratory
Open Date: November 14, 2025
Close Date: January 30, 2026
Status: Posted
CFDA Numbers: 81.089
Improving Efficiency, Reliability, and Flexibility of Coal-Based Power Plants
Deadline: January 7, 2026
Opportunity Number: DE-FOA-0003606
Agency: National Energy Technology Laboratory
Open Date: October 31, 2025
Close Date: January 7, 2026
Status: Posted
CFDA Numbers: 81.089
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program
Deadline: September 30, 2026
Opportunity Number: DE-FOA-0003600
Agency: Office of Science
Open Date: September 30, 2025
Close Date: September 30, 2026
Status: Posted
CFDA Numbers: 81.049
Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)
Deadline: June 7, 2028
Opportunity Number: PAR-25-449
Agency: National Institutes of Health
Open Date: September 26, 2025
Close Date: June 7, 2028
Status: Posted
CFDA Numbers: 93.213
Dynamic and Adaptable Infrastructure for Drug Development and Outreach to Aid the Research Community in Advancing Medication Repurposing and Repositioning Efforts for Substance Use Disorders (SUDs) (U54 - Clinical Trials Not Allowed)
Deadline: January 28, 2026
Opportunity Number: RFA-DA-26-020
Agency: National Institutes of Health
Open Date: September 24, 2025
Close Date: January 28, 2026
Status: Posted
CFDA Numbers: 93.279
Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
Deadline: July 20, 2028
Opportunity Number: PAR-25-450
Agency: National Institutes of Health
Open Date: September 22, 2025
Close Date: July 20, 2028
Status: Posted
CFDA Numbers: 93.350, 93.865
NHLBI TOPMed: Omics Phenotypes of Heart, Lung, and Blood Disorders (X01 - Clinical Trial Not Allowed)
Deadline: May 8, 2028
Opportunity Number: PAR-25-447
Agency: National Institutes of Health
Open Date: September 22, 2025
Close Date: May 8, 2028
Status: Posted
CFDA Numbers: 93.837, 93.838, 93.839, 93.840, 93.233
Advancing Research on the Application of Digital Health Technology to the Management of Type 2 Diabetes (R01- Clinical Trail Required)
Deadline: October 6, 2026
Opportunity Number: RFA-DK-26-315
Agency: National Institutes of Health
Open Date: September 17, 2025
Close Date: October 6, 2026
Status: Posted
CFDA Numbers: 93.847
Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional)
Deadline: May 7, 2028
Opportunity Number: PAR-25-439
Agency: National Institutes of Health
Open Date: September 17, 2025
Close Date: May 7, 2028
Status: Posted
CFDA Numbers: 93.361
BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)
Deadline: November 8, 2027
Opportunity Number: RFA-DA-27-004
Agency: National Institutes of Health
Open Date: September 16, 2025
Close Date: November 8, 2027
Status: Posted
CFDA Numbers: 93.213, 93.867, 93.853, 93.866, 93.242, 93.273, 93.279, 93.286, 93.372, 93.173, 93.865
NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)
Deadline: June 2, 2028
Opportunity Number: PAR-25-445
Agency: National Institutes of Health
Open Date: September 15, 2025
Close Date: June 2, 2028
Status: Posted
CFDA Numbers: 93.173
Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
Deadline: August 21, 2028
Opportunity Number: PAR-25-446
Agency: National Institutes of Health
Open Date: September 10, 2025
Close Date: August 21, 2028
Status: Posted
CFDA Numbers: 93.279
F25AS00282 National Fish Passage Program FY25
Deadline: December 31, 2025
Opportunity Number: F25AS00282
Agency: Fish and Wildlife Service
Open Date: September 3, 2025
Close Date: December 31, 2025
Status: Posted
CFDA Numbers: 15.685
NIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program (R25 Independent Clinical Trial Not Allowed)
Deadline: May 26, 2027
Opportunity Number: RFA-AG-26-010
Agency: National Institutes of Health
Open Date: September 2, 2025
Close Date: May 26, 2027
Status: Posted
CFDA Numbers: 93.866