Open for applications

Federal funding opportunity

Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)

National Institutes of Health

  • OpportunityRFA-DK-27-119
  • Agency codeHHS-NIH11
  • CategoryDiscretionary (D)
173 days until applications close Wed, February 10, 2027
PostedJun 16, 2026 ClosesFeb 10, 2027
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Competitive proposals usually start 6+ weeks out.

$4.8M Est. program funding
$750,000 Award ceiling
N/a Award floor
4 Expected no. of awards

Program summary

Synopsis

This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.

Timeline

Key dates

  • June 16, 2026
    Opportunity posted to grants.gov
  • August 21, 2026
    Today — 173 days of the window remain
  • February 10, 2027
    Applications close
  • April 10, 2027
    Opportunity archived

Who may apply

Eligibility

Eligible applicant types as published by the awarding agency:

  • County governments
  • Small businesses
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Private institutions of higher education
  • Independent school districts
  • Public housing authorities/Indian housing authorities
  • State governments
  • Native American tribal governments (Federally recognized)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • City or township governments
  • Public and State controlled institutions of higher education
  • For profit organizations other than small businesses
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional info on eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Only institutions at which there is a strong ongoing base of digestive and/or liver diseases-relevant research that relates to the proposed theme of the Center are eligible. The already funded research base must have at least $3 million per year in direct costs of supported research within a proposed theme area that is of primary interest to the NIDDK. These may be a mix of Federal and privately funded research awards or research career development awards. However, at least 30 percent of the total funding contributing to the research base must be secured from the NIDDK. Moreover, enough awards within the research base must be Federal to fulfill the requirement that each Biomedical Research Core must be utilized by a minimum of two federally funded Center members. Training grants, education grants, and fellowship awards are not considered part of the research base funding. Since "Facilities and Administration" costs vary considerably between institutions, these must not be included in the calculation of the research base.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Cost sharing or matching
Not required

Awarding agency

Additional information

Agency name
National Institutes of Health
Grantor contact
National Institutes of Health
301-402-2541
NIDDK_DDN@nih.gov

Assistance listing

CFDA program(s)

  • 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research

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