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Total Dollars Available
$ 100 Trillion

ROSES 2025: Research Opportunities in Space and Earth Science

Deadline: May 31, 2026


Opportunity Number: NNH25ZDA001N

Agency: NASA Headquarters

Open Date: July 11, 2025

Close Date: May 31, 2026

Status: Posted

CFDA Numbers: 43.001

Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)

Deadline: February 8, 2028


Opportunity Number: RFA-FD-25-017

Agency: Food and Drug Administration

Open Date: July 11, 2025

Close Date: February 8, 2028

Status: Posted

CFDA Numbers: 93.103

Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)

Deadline: May 16, 2028


Opportunity Number: RFA-FD-25-020

Agency: Food and Drug Administration

Open Date: July 11, 2025

Close Date: May 16, 2028

Status: Posted

CFDA Numbers: 93.103

National Science Foundation Translation to Practice

Deadline: May 19, 2026


Opportunity Number: 25-540

Agency: U.S. National Science Foundation

Open Date: July 9, 2025

Close Date: May 19, 2026

Status: Posted

CFDA Numbers: 47.079, 47.083, 47.041, 47.074, 47.084, 47.049, 47.050, 47.070, 47.075, 47.076

FY25 ONR Office Of Naval Research (ONR) Science, Technology, Engineering, and Mathematics(STEM) Education and Workforce Program

Deadline: June 30, 2026


Opportunity Number: N0001425SF006

Agency: Office of Naval Research

Open Date: July 7, 2025

Close Date: June 30, 2026

Status: Posted

CFDA Numbers: 12.330

FY25 Naval Air Warfare Center Aircraft Division Office-Wide Broad Agency Announcement

Deadline: June 22, 2026


Opportunity Number: N00421-25-S-0001

Agency: NAVAIR

Open Date: June 27, 2025

Close Date: June 22, 2026

Status: Posted

CFDA Numbers: 12.300

Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives Clinical Trials Not Allowed

Deadline: April 1, 2027


Opportunity Number: PAR-25-003

Agency: Food and Drug Administration

Open Date: June 25, 2025

Close Date: April 1, 2027

Status: Posted

CFDA Numbers: 93.103

Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial Optional)

Deadline: July 14, 2026


Opportunity Number: RFA-OD-25-008

Agency: National Institutes of Health

Open Date: June 24, 2025

Close Date: July 14, 2026

Status: Posted

CFDA Numbers: 93.077

TTO Office Wide (OW) BAA 2025

Deadline: December 22, 2026


Opportunity Number: HR001125S0011

Agency: DARPA - Tactical Technology Office

Open Date: June 23, 2025

Close Date: December 22, 2026

Status: Posted

CFDA Numbers: 12.910

Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed)

Deadline: March 1, 2028


Opportunity Number: PAR-25-437

Agency: National Institutes of Health

Open Date: June 18, 2025

Close Date: March 1, 2028

Status: Posted

CFDA Numbers: 93.310

Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)

Deadline: January 28, 2028


Opportunity Number: PAR-25-383

Agency: National Institutes of Health

Open Date: June 17, 2025

Close Date: January 28, 2028

Status: Posted

CFDA Numbers: 93.279, 93.242, 93.865, 93.286, 93.853, 93.867, 93.866, 93.121, 93.213, 93.273

Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Deadline: February 17, 2028


Opportunity Number: PAR-25-442

Agency: National Institutes of Health

Open Date: June 17, 2025

Close Date: February 17, 2028

Status: Posted

CFDA Numbers: 93.350, 93.121, 93.867, 93.855, 93.865, 93.242

NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

Deadline: May 7, 2028


Opportunity Number: PAR-25-333

Agency: National Institutes of Health

Open Date: June 17, 2025

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.121

Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)

Deadline: September 7, 2028


Opportunity Number: PAR-25-415

Agency: National Institutes of Health

Open Date: June 13, 2025

Close Date: September 7, 2028

Status: Posted

CFDA Numbers: 93.859, 93.242, 93.867, 93.307, 93.173, 93.361, 93.273, 93.279, 93.866, 93.879, 93.846, 93.113, 93.172, 93.853, 93.121, 93.286, 93.865, 93.398, 93.847, 93.855

Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)

Deadline: September 7, 2028


Opportunity Number: PAR-25-414

Agency: National Institutes of Health

Open Date: June 13, 2025

Close Date: September 7, 2028

Status: Posted

CFDA Numbers: 93.866, 93.279, 93.398, 93.273, 93.846, 93.121, 93.286, 93.307, 93.879, 93.853, 93.172, 93.242, 93.859, 93.113, 93.173, 93.361, 93.867, 93.847, 93.855, 93.865

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Deadline: May 7, 2028


Opportunity Number: PA-25-425

Agency: National Institutes of Health

Open Date: June 12, 2025

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.398, 93.855, 93.839, 93.242, 93.113, 93.173, 93.213, 93.846, 93.867, 93.840, 93.286, 93.310, 93.847, 93.233, 93.837, 93.279, 93.307, 93.361, 93.865, 93.121, 93.859, 93.273, 93.838, 93.866, 93.853

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Deadline: May 7, 2028


Opportunity Number: PA-25-426

Agency: National Institutes of Health

Open Date: June 12, 2025

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.837, 93.867, 93.121, 93.840, 93.242, 93.113, 93.273, 93.173, 93.213, 93.839, 93.855, 93.847, 93.307, 93.361, 93.865, 93.233, 93.838, 93.279, 93.310, 93.398, 93.866

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)

Deadline: May 7, 2028


Opportunity Number: PA-25-423

Agency: National Institutes of Health

Open Date: June 12, 2025

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.361, 93.859, 93.866, 93.121, 93.839, 93.233, 93.865, 93.113, 93.242, 93.172, 93.173, 93.838, 93.846, 93.840, 93.279, 93.307, 93.847, 93.867, 93.213, 93.837, 93.273, 93.286, 93.310, 93.855

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

Deadline: May 7, 2028


Opportunity Number: PA-25-422

Agency: National Institutes of Health

Open Date: June 12, 2025

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.398, 93.855, 93.839, 93.233, 93.113, 93.172, 93.173, 93.846, 93.879, 93.840, 93.286, 93.310, 93.847, 93.213, 93.837, 93.279, 93.307, 93.361, 93.866, 93.121, 93.865, 93.273, 93.838, 93.867, 93.853

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)

Deadline: May 7, 2028


Opportunity Number: PA-25-424

Agency: National Institutes of Health

Open Date: June 12, 2025

Close Date: May 7, 2028

Status: Posted

CFDA Numbers: 93.859, 93.840, 93.279, 93.233, 93.310, 93.113, 93.121, 93.837, 93.838, 93.839, 93.846

NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)

Deadline: June 14, 2027


Opportunity Number: PAR-25-416

Agency: National Institutes of Health

Open Date: June 11, 2025

Close Date: June 14, 2027

Status: Posted

CFDA Numbers: 93.859

NSF-DFG Lead Agency Opportunity in Chemistry and Chemical Process and Transport Systems

No deadline specified


Opportunity Number: 25-537

Agency: U.S. National Science Foundation

Open Date: June 6, 2025

Status: Posted

CFDA Numbers: 47.041, 47.049

EDA FY25 Disaster Supplemental

No deadline specified


Opportunity Number: EDA-DISASTER-2025

Agency: Economic Development Administration

Open Date: June 4, 2025

Status: Posted

CFDA Numbers: 11.307

Defense Sciences Office (DSO) Office-wide BAA

Deadline: June 2, 2026


Opportunity Number: HR001125S0013

Agency: DARPA - Defense Sciences Office

Open Date: June 3, 2025

Close Date: June 2, 2026

Status: Posted

CFDA Numbers: 12.910

Staff Research Program

Deadline: June 2, 2030


Opportunity Number: W911NF25S0007

Agency: Dept of the Army -- Materiel Command

Open Date: June 3, 2025

Close Date: June 2, 2030

Status: Posted

CFDA Numbers: 12.431

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