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$ 100 Trillion
Total Dollars Available

Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)

Deadline: January 7, 2028


Opportunity Number: PAR-25-206

Agency: National Institutes of Health

Open Date: October 31, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.242

Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

Deadline: January 7, 2028


Opportunity Number: PAR-25-233

Agency: National Institutes of Health

Open Date: October 30, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.399, 93.242, 93.121, 93.279, 93.310, 93.113, 93.853, 93.172, 93.989, 93.273, 93.865, 93.866

Natural Product Multi-Site Clinical Trial Data Coordinating Center (Collaborative U24 Clinical Trial Required)

Deadline: July 14, 2026


Opportunity Number: PAR-24-313

Agency: National Institutes of Health

Open Date: October 30, 2024

Close Date: July 14, 2026

Status: Posted

CFDA Numbers: 93.213

Screening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)

Deadline: January 7, 2028


Opportunity Number: PAR-25-185

Agency: National Institutes of Health

Open Date: October 30, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.865, 93.121, 93.351

Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)

Deadline: July 14, 2026


Opportunity Number: PAR-24-312

Agency: National Institutes of Health

Open Date: October 29, 2024

Close Date: July 14, 2026

Status: Posted

CFDA Numbers: 93.213

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

Deadline: April 15, 2027


Opportunity Number: PAR-25-131

Agency: National Institutes of Health

Open Date: October 29, 2024

Close Date: April 15, 2027

Status: Posted

CFDA Numbers: 93.879

Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)

Deadline: January 7, 2028


Opportunity Number: PAR-25-144

Agency: National Institutes of Health

Open Date: October 29, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.279, 93.242, 93.273, 93.866, 93.847, 93.307, 93.172, 93.846, 93.399, 93.853, 93.837, 93.361, 93.867, 93.855, 93.213, 93.121, 93.865, 93.113, 93.839, 93.840, 93.233, 93.838, 93.310

Translational Neural Devices (R61/R33 - Clinical Trial Optional)

Deadline: January 28, 2027


Opportunity Number: PAR-25-053

Agency: National Institutes of Health

Open Date: October 29, 2024

Close Date: January 28, 2027

Status: Posted

CFDA Numbers: 93.853

Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

Deadline: January 7, 2028


Opportunity Number: PAR-25-024

Agency: National Institutes of Health

Open Date: October 28, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.853, 93.866

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

Deadline: November 5, 2027


Opportunity Number: PAR-25-149

Agency: National Institutes of Health

Open Date: October 28, 2024

Close Date: November 5, 2027

Status: Posted

CFDA Numbers: 93.853

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)

Deadline: November 16, 2027


Opportunity Number: PAR-25-122

Agency: National Institutes of Health

Open Date: October 28, 2024

Close Date: November 16, 2027

Status: Posted

CFDA Numbers: 93.121, 93.853, 93.173, 93.350, 93.855, 93.242

BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)

Deadline: June 15, 2027


Opportunity Number: RFA-MH-26-140

Agency: National Institutes of Health

Open Date: October 23, 2024

Close Date: June 15, 2027

Status: Posted

CFDA Numbers: 93.286, 93.173, 93.867, 93.213, 93.273, 93.853, 93.866, 93.242, 93.865

NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Deadline: January 6, 2028


Opportunity Number: PAR-25-057

Agency: National Institutes of Health

Open Date: October 23, 2024

Close Date: January 6, 2028

Status: Posted

CFDA Numbers: 93.121

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)

Deadline: October 20, 2027


Opportunity Number: PAR-25-060

Agency: National Institutes of Health

Open Date: October 22, 2024

Close Date: October 20, 2027

Status: Posted

CFDA Numbers: 93.853

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)

Deadline: October 20, 2027


Opportunity Number: PAR-25-059

Agency: National Institutes of Health

Open Date: October 22, 2024

Close Date: October 20, 2027

Status: Posted

CFDA Numbers: 93.853

NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)

Deadline: October 15, 2027


Opportunity Number: PAR-25-120

Agency: National Institutes of Health

Open Date: October 18, 2024

Close Date: October 15, 2027

Status: Posted

CFDA Numbers: 93.173

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)

Deadline: October 14, 2026


Opportunity Number: PAR-25-074

Agency: National Institutes of Health

Open Date: October 15, 2024

Close Date: October 14, 2026

Status: Posted

CFDA Numbers: 93.394

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)

Deadline: October 14, 2026


Opportunity Number: PAR-25-075

Agency: National Institutes of Health

Open Date: October 15, 2024

Close Date: October 14, 2026

Status: Posted

CFDA Numbers: 93.394

Data Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative U24 Clinical Trial Required)

Deadline: July 14, 2026


Opportunity Number: PAR-24-276

Agency: National Institutes of Health

Open Date: October 15, 2024

Close Date: July 14, 2026

Status: Posted

CFDA Numbers: 93.213

Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)

Deadline: January 6, 2028


Opportunity Number: PAR-25-062

Agency: National Institutes of Health

Open Date: October 10, 2024

Close Date: January 6, 2028

Status: Posted

CFDA Numbers: 93.121

Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)

Deadline: January 7, 2027


Opportunity Number: PAR-25-098

Agency: National Institutes of Health

Open Date: October 10, 2024

Close Date: January 7, 2027

Status: Posted

CFDA Numbers: 93.399, 93.307, 93.121, 93.313

Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)

Deadline: October 14, 2026


Opportunity Number: PAR-24-304

Agency: National Institutes of Health

Open Date: October 10, 2024

Close Date: October 14, 2026

Status: Posted

CFDA Numbers: 93.394

Occupational Safety and Health Education and Research Centers (T42)

Deadline: October 26, 2028


Opportunity Number: RFA-OH-25-002

Agency: Centers for Disease Control and Prevention - ERA

Open Date: October 7, 2024

Close Date: October 26, 2028

Status: Posted

CFDA Numbers: 93.262

Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)

Deadline: January 7, 2028


Opportunity Number: PA-25-093

Agency: National Institutes of Health

Open Date: October 4, 2024

Close Date: January 7, 2028

Status: Posted

CFDA Numbers: 93.855, 93.846

Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders(U01 Clinical Trial Optional)

Deadline: June 22, 2026


Opportunity Number: PAR-25-050

Agency: National Institutes of Health

Open Date: October 2, 2024

Close Date: June 22, 2026

Status: Posted

CFDA Numbers: 93.853

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