Synopsis

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.
Response Date	Jul 05, 2029 12:00:00 AM EDT
Posting Date	May 04, 2026 12:00:00 AM EDT
Archive Date	Sep 05, 2029 12:00:00 AM EDT
Award Ceiling	500,000
Award Floor	N/a
Cost Sharing	No

Eligibility

Eligible Applicants

Others (see text field entitled "Additional Information on Eligibility" for clarification), Independent school districts, County governments, Public and State controlled institutions of higher education, City or township governments, Native American tribal organizations (other than Federally recognized tribal governments), Special district governments, Small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Public housing authorities/Indian housing authorities, Private institutions of higher education, Native American tribal governments (Federally recognized), For profit organizations other than small businesses, State governments

Additional Info on Eligibility:

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	N/a
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

• 93.393: Cancer Cause and Prevention Research
• 93.394: Cancer Detection and Diagnosis Research
• 93.395: Cancer Treatment Research
• 93.396: Cancer Biology Research
• 93.399: Cancer Control
• 93.865: Child Health and Human Development Extramural Research
• 93.867: Vision Research