Synopsis

Current recipients of specific types of NIH research grants may apply for administrative supplements, using this Notice of Funding Opportunity (NOFO), to provide additional funding to a currently funded grant to meet increased costs that are within the scope of the peer-reviewed and approved project, but that were unforeseen when the new or competing renewal application was awarded. Applications for administrative supplements are considered prior approval requests (as described in Section 8.1.2.11 of the NIH Grants Policy Statement) and will be routed directly to the Grants Management Officer of the parent award. There is no guarantee that funds are available from the awarding IC or for any specific grant. Therefore, prior to submission, applicants must discuss potential requests with the awarding ICO grants and program officials.
Response Date	Nov 30, 2028 12:00:00 AM EST
Posting Date	Nov 26, 2025 12:00:00 AM EST
Archive Date	Jan 04, 2029 12:00:00 AM EST
Award Ceiling	N/a
Award Floor	N/a
Cost Sharing	No

Eligibility

Eligible Applicants

State governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), Native American tribal organizations (other than Federally recognized tribal governments), For profit organizations other than small businesses, Independent school districts, Public housing authorities/Indian housing authorities, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, City or township governments, Small businesses, Special district governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, County governments, Private institutions of higher education, Native American tribal governments (Federally recognized), Public and State controlled institutions of higher education

Additional Info on Eligibility:

Other Eligible Applicants: Indian/Native American Tribal Governments (Other than Federally Recognized); Eligible Agencies of the Federal Government; U.S. Territory or Possession; Faith-based or Community-based Organizations; Regional Organizations; Non-domestic (non-U.S.) Entities (Foreign Organizations). Reminder: This NOFO supports administrative supplements to existing projects. To be eligible, the parent award must be active (i.e., not in a co-cost extension), and the research proposed in the supplement must be accomplished within the competitive segment. The proposed supplement must be to provide for an increase in costs due to unforeseen circumstances. All additional costs must be within the scope of the peer reviewed and approved project. IMPORTANT: The research proposed in the supplement application must be within the peer-reviewed scope of the NIH-supported grant project. Foreign Organizations/International Collaborations: All activities with foreign institutions must align with existing parent award. NIH will no longer issue awards (new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025. Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	N/a
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

• 93.113: Environmental Health
• 93.121: Oral Diseases and Disorders Research
• 93.142: NIEHS Hazardous Waste Worker Health and Safety Training
• 93.143: NIEHS Superfund Hazardous Substances_Basic Research and Education
• 93.172: Human Genome Research
• 93.173: Research Related to Deafness and Communication Disorders
• 93.213: Research and Training in Complementary and Integrative Health
• 93.233: National Center on Sleep Disorders Research
• 93.242: Mental Health Research Grants
• 93.273: Alcohol Research Programs
• 93.279: Drug Use and Addiction Research Programs
• 93.286: Discovery and Applied Research for Technological Innovations to Improve Human Health
• 93.307: Minority Health and Health Disparities Research
• 93.310: Trans-NIH Research Support
• 93.313: NIH Office of Research on Women's Health
• 93.350: National Center for Advancing Translational Sciences
• 93.351: Research Infrastructure Programs
• 93.361: Nursing Research
• 93.372: 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies
• 93.393: Cancer Cause and Prevention Research
• 93.394: Cancer Detection and Diagnosis Research
• 93.395: Cancer Treatment Research
• 93.396: Cancer Biology Research
• 93.399: Cancer Control
• 93.837: Cardiovascular Diseases Research
• 93.838: Lung Diseases Research
• 93.839: Blood Diseases and Resources Research
• 93.840: Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
• 93.846: Arthritis, Musculoskeletal and Skin Diseases Research
• 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research
• 93.853: Extramural Research Programs in the Neurosciences and Neurological Disorders
• 93.855: Allergy and Infectious Diseases Research
• 93.859: Biomedical Research and Research Training
• 93.865: Child Health and Human Development Extramural Research
• 93.866: Aging Research
• 93.867: Vision Research
• 93.879: Medical Library Assistance
• 93.989: International Research and Research Training
• 93.ECH: Environmental influences on Child Health Outcomes (ECHO) Program