View Grant Opportunity

Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)

National Institutes of Health

RFA-AI-27-019

HHS-NIH11

General Information

$9,600,000
Est. Program Funding:
June 4, 2026
Closing Date:
3
Expected No. of Awards
$3,000,000
Award Ceiling

Opportunity Number:
RFA-AI-27-019

Owning Agency:
HHS-NIH11

Opportunity Category:
Discretionary (D)

Synopsis

The purpose of this notice of funding opportunity (NOFO) is to support the establishment or continuation of longitudinal infant cohorts to determine and compare how initial and repeated natural influenza infections and/or influenza vaccinations shape infant and childhood immunity to future influenza exposures. The goal of this research is to understand how these exposures influence immune responses to subsequent influenza infections and/or vaccines and provide key information to facilitate design of durable, broadly protective influenza vaccines.
Response Date Jun 04, 2026 12:00:00 AM EDT
Posting Date Feb 10, 2026 12:00:00 AM EST
Archive Date Aug 03, 2026 12:00:00 AM EDT
Award Ceiling 3,000,000
Award Floor N/a
Cost Sharing No

Eligibility

Eligible Applicants City or township governments, Independent school districts, Native American tribal organizations (other than Federally recognized tribal governments), Small businesses, Public housing authorities/Indian housing authorities, Others (see text field entitled "Additional Information on Eligibility" for clarification), Special district governments, County governments, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, Private institutions of higher education, For profit organizations other than small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Info on Eligibility: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Additional Information

Agency Name National Institutes of Health
Link to Additional Information: N/a
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk
Phone: 301-402-2541

CFDA Program(s)

  • 93.855: Allergy and Infectious Diseases Research
   

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