Synopsis

The Commercialization Readiness Pilot (CRP) program helps small business concerns (SBCs) move NIH-funded SBIR or STTR projects from late-stage development to commercialization. The CRP supports later-stage research and development (R&D) and/or technical assistance that Phase II and Phase IIB Strategic Breakthrough awards do not typically support. This includes:Independent replication or confirmation of key studiesIND- or IDE-enabling studiesClinical studiesManufacturing scale-up and related quality activitiesRegulatory and other specialized technical supportSBCs may subcontract (outsource) a significant amount of the work in a CRP to meet the project goals.
Response Date	Apr 05, 2027 12:00:00 AM EDT
Posting Date	May 28, 2026 12:00:00 AM EDT
Archive Date	Jun 04, 2029 12:00:00 AM EDT
Award Ceiling	N/a
Award Floor	N/a
Cost Sharing	No

Eligibility

Eligible Applicants

County governments, Independent school districts, Special district governments, Small businesses, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, City or township governments, Native American tribal organizations (other than Federally recognized tribal governments), State governments, Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification)

Additional Info on Eligibility:

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	N/a
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

• 93.113: Environmental Health
• 93.121: Oral Diseases and Disorders Research
• 93.143: NIEHS Superfund Hazardous Substances_Basic Research and Education
• 93.172: Human Genome Research
• 93.173: Research Related to Deafness and Communication Disorders
• 93.233: National Center on Sleep Disorders Research
• 93.242: Mental Health Research Grants
• 93.273: Alcohol Research Programs
• 93.286: Discovery and Applied Research for Technological Innovations to Improve Human Health
• 93.307: Minority Health and Health Disparities Research
• 93.313: NIH Office of Research on Women's Health
• 93.350: National Center for Advancing Translational Sciences
• 93.351: Research Infrastructure Programs
• 93.393: Cancer Cause and Prevention Research
• 93.394: Cancer Detection and Diagnosis Research
• 93.395: Cancer Treatment Research
• 93.837: Cardiovascular Diseases Research
• 93.838: Lung Diseases Research
• 93.839: Blood Diseases and Resources Research
• 93.840: Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
• 93.846: Arthritis, Musculoskeletal and Skin Diseases Research
• 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research
• 93.853: Extramural Research Programs in the Neurosciences and Neurological Disorders
• 93.855: Allergy and Infectious Diseases Research
• 93.859: Biomedical Research and Research Training
• 93.865: Child Health and Human Development Extramural Research
• 93.866: Aging Research
• 93.867: Vision Research