Synopsis

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Response Date	Oct 30, 2026 12:00:00 AM EDT
Posting Date	Jun 18, 2026 12:00:00 AM EDT
Archive Date	Dec 09, 2026 12:00:00 AM EST
Award Ceiling	500,000
Award Floor	3
Cost Sharing	No

Eligibility

Eligible Applicants

Public housing authorities/Indian housing authorities, County governments, Native American tribal governments (Federally recognized), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Special district governments, City or township governments, Private institutions of higher education, Public and State controlled institutions of higher education, Independent school districts, Small businesses, Native American tribal organizations (other than Federally recognized tribal governments), For profit organizations other than small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification)

Additional Info on Eligibility:

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	N/a
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

• 93.172: Human Genome Research