Synopsis

This Notice of Funding Opportunity seeks applications to establish and operate a dynamic and adaptable drug development infrastructure to support the research community. The aim is to strengthen and expand the substance use disorder (SUD) drug development pipeline by accelerating the evaluation and validation of repurposed and repositioned drugs. The Center and its team of subject matter experts will provide comprehensive drug development services to academic and biotech researchers at all stages of product development. By supporting various projects that address different SUD indications, the Center will contribute to reducing the burden of SUDs on individuals and communities. The services offered will include assistance in creating Target Product Profiles, Freedom-to-Operate analysis, intellectual property consultations, regulatory guidance, and technical pipeline support. Additionally, the Center will engage in outreach efforts to connect with the research community, solicit proposals, and implement processes to evaluate, select, and advance the projects focused on repurposing and repositioning medications for SUD treatment.
Response Date	Jan 28, 2026 12:00:00 AM EST
Posting Date	Sep 24, 2025 12:00:00 AM EDT
Archive Date	Mar 05, 2026 12:00:00 AM EST
Award Ceiling	N/a
Award Floor	N/a
Cost Sharing	No

Eligibility

Eligible Applicants

State governments, County governments, Public housing authorities/Indian housing authorities, Others (see text field entitled "Additional Information on Eligibility" for clarification), For profit organizations other than small businesses, Independent school districts, Native American tribal governments (Federally recognized), City or township governments, Special district governments, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Public and State controlled institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Small businesses

Additional Info on Eligibility:

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-020.html
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

• 93.279: Drug Use and Addiction Research Programs