Synopsis

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction.
Response Date	Aug 25, 2028 12:00:00 AM EDT
Posting Date	Aug 25, 2025 12:00:00 AM EDT
Archive Date	Sep 30, 2028 12:00:00 AM EDT
Award Ceiling	N/a
Award Floor	N/a
Cost Sharing	No

Eligibility

Eligible Applicants

Small businesses, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, County governments, Private institutions of higher education, State governments, Public housing authorities/Indian housing authorities, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Special district governments, City or township governments, Public and State controlled institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), Independent school districts, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses

Additional Info on Eligibility:

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name	National Institutes of Health
Link to Additional Information:	https://grants.nih.gov/grants/guide/pa-files/PAR-25-322.html
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk Phone: 301-402-2541

CFDA Program(s)

• 93.113: Environmental Health
• 93.121: Oral Diseases and Disorders Research
• 93.172: Human Genome Research
• 93.173: Research Related to Deafness and Communication Disorders
• 93.213: Research and Training in Complementary and Integrative Health
• 93.233: National Center on Sleep Disorders Research
• 93.242: Mental Health Research Grants
• 93.273: Alcohol Research Programs
• 93.286: Discovery and Applied Research for Technological Innovations to Improve Human Health
• 93.307: Minority Health and Health Disparities Research
• 93.313: NIH Office of Research on Women's Health
• 93.351: Research Infrastructure Programs
• 93.361: Nursing Research
• 93.393: Cancer Cause and Prevention Research
• 93.398: Cancer Research Manpower
• 93.837: Cardiovascular Diseases Research
• 93.838: Lung Diseases Research
• 93.839: Blood Diseases and Resources Research
• 93.840: Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
• 93.846: Arthritis, Musculoskeletal and Skin Diseases Research
• 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research
• 93.855: Allergy and Infectious Diseases Research
• 93.865: Child Health and Human Development Extramural Research
• 93.866: Aging Research
• 93.867: Vision Research
• 93.879: Medical Library Assistance