View Grant Opportunity
NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
National Institutes of Health
PAR-25-049
HHS-NIH11
General Information
Est. Program Funding:
Closing Date:
Expected No. of Awards
Award Ceiling
Opportunity Number:
PAR-25-049
Owning Agency:
HHS-NIH11
Opportunity Category:
Discretionary (D)
Synopsis
This announcement (NOFO) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA. |
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| Response Date | Jul 09, 2026 12:00:00 AM EDT |
| Posting Date | Nov 07, 2024 12:00:00 AM EST |
| Archive Date | Aug 08, 2026 12:00:00 AM EDT |
| Award Ceiling | N/a |
| Award Floor | N/a |
| Cost Sharing | No |
Eligibility
| Eligible Applicants | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, City or township governments, Small businesses, County governments, Special district governments, Private institutions of higher education, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, State governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), Independent school districts, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, Native American tribal organizations (other than Federally recognized tribal governments), Native American tribal governments (Federally recognized) |
| Additional Info on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name | National Institutes of Health |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-049.html |
| Grantor Contact Information: |
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CFDA Program(s)
- 93.853: Extramural Research Programs in the Neurosciences and Neurological Disorders
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