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Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

National Institutes of Health

PAR-25-145

HHS-NIH11

General Information

N/a
Est. Program Funding:
January 7, 2028
Closing Date:
N/a
Expected No. of Awards
N/a
Award Ceiling

Opportunity Number:
PAR-25-145

Owning Agency:
HHS-NIH11

Opportunity Category:
Discretionary (D)

Synopsis

The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae. Research projects should focus on mechanistic studies with translational endpoints and longitudinal clinical phenotyping to identify and validate clinical endpoints (biomarkers, imaging, patient-reported outcomes, or combined elements) for future use in clinical trials that will evaluate the efficacy of interventions designed to prevent or reduce specific adverse sequelae.
Response Date Jan 07, 2028 12:00:00 AM EST
Posting Date Nov 06, 2024 12:00:00 AM EST
Archive Date Feb 12, 2028 12:00:00 AM EST
Award Ceiling N/a
Award Floor N/a
Cost Sharing No

Eligibility

Eligible Applicants Native American tribal governments (Federally recognized), Others (see text field entitled "Additional Information on Eligibility" for clarification), Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, State governments, Small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, County governments, City or township governments, Special district governments, Independent school districts, Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Public and State controlled institutions of higher education
Additional Info on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name National Institutes of Health
Link to Additional Information: https://grants.nih.gov/grants/guide/pa-files/PAR-25-145.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact: GrantSolutions Help Desk
Phone: 301-402-2541

CFDA Program(s)

  • 93.393: Cancer Cause and Prevention Research
   

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